Searchable abstracts of presentations at key conferences in endocrinology

ea0016p113 | Clinical cases | ECE2008

Unresectable huge sternal and mediastinal metastasis of follicular thyroid carcinoma; radiotherapy as first-line and palliative therapy

Demirer Asli Nar , Ayturk Semra , Tutuncu Neslihan Bascil , Gursoy Alptekin , Pak Yucel , Demirag Nilgun Guvener

Distant metastases as initial manifestation of follicular thyroid carcinoma is rare. We report a case of an unusual initial presentation of follicular thyroid carcinoma on follow-up. A 52-year-old woman presented with a 12-month history of progressively enlarging mass in the anterior chest wall. The mass was fixed to the chest wall, measuring 12×10 cm in diameter. Computed tomography demonstrated a lobulated soft-tissue mass (17×11×6 cm) destructing sternum and ...

ea0016p690 | Thyroid | ECE2008

Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease

Demirer Asli Nar , Kemal Yasemin , Tutuncu Neslihan Bascil , Gursoy Alptekin , Demirag Nilgun Guvener

Objective: Our aim was to determine the prevalence and clinicopathological characteristics of thyroid cancers in the dialysis population and to evaluate potential risk factors.Design: We performed a retrospective analysis of our end-stage renal disease (ESRD) patients on dialysis and thyroidectomized patients without ESRD (2000–2006). Then we compared the data of thyroid cancer patients on dialysis (n=9) with the data of patients who had hist...

ea0016p694 | Thyroid | ECE2008

Cyclin A and B1 are overexpressed in thyroid cancers which had been operated for indeterminate, nondiagnostic, or suspicious fine-needle aspirate results

Demirer Asli Nar , Ozen Ozlem , Sengul Aysegul , Tutuncu Neslihan Bascil , Gursoy Alptekin , Demirag Nilgun Guvener

Objective: Approximately 30% of patients with thyroid nodules have indeterminate, nondiagnostic, or suspicious fine-needle aspiration (FNA) biopsy results. These patients usually undergo thyroidectomy because of cancer risk. Our aim was to determine diagnostic markers to distinguish benign from malignant thyroid neoplasms, so we focused on G2-M boundary regulators of the cell cycle and investigated the expression of two proteins, cyclin A and cyclin B1.M...